Organic Acids

Organic compounds with acidic properties, organic acids are generally weak acids incapable of complete dissociation in water. Available in a range of chemical compositions and acid strengths, they can be used for various industrial and everyday applications.

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3,076 – 3,090 of 4,347 results

3,076

Apexbio Technology LLC ENMD-2076 934353-76-1 50mg

ENMD-2076 (CAS 934353-76-1) is a selective inhibitor of Aurora A kinase (IC50 14 nM) and FLT3 (IC50 1 86 nM) with additional inhibitory activity against multiple tyrosine kinases implicated in angiogenesis and cell proliferation including RET FLT4/VEGFR3 SRC CSF1R NTRK1 FGFR1/2 VEGFR2/KDR LCK and PDGFR (IC50 1 86 120 nM) ENMD-2076 disrupts cell cycle progression by arresting cells in the G2/M phase through inhibition of Aurora kinases suppresses the PI3K/AKT signaling pathway and demonstrates cytotoxic effects in hematologic malignancy and solid tumor cell lines (in vitro IC50 25 700 nM) In vivo it reduces tumor growth and angiogenesis in xenograft models supporting its use in cancer research and antiangiogenic studies

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3,077

Apexbio Technology LLC FSLLRY-NH2 TFA 245329-02-6 (free base) 25mg

FSLLRY-NH2 TFA is a synthetic peptide antagonist targeting protease-activated receptor 2 (PAR-2) It is designed to block PAR-2 activation thereby inhibiting intracellular signaling cascades such as calcium mobilization and MAP kinase activation that underlie inflammatory responses nociceptive transmission and immune modulation FSLLRY-NH2 TFA exerts its biological activity primarily through competitive binding to PAR-2 preventing receptor activation and downstream signaling events Based on these pharmacological properties FSLLRY-NH2 TFA holds research potential in the study of inflammation-associated disorders and pain pathways

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3,078

Apexbio Technology LLC Prasugrel hydrochloride 389574-19-0 100mg

Prasugrel hydrochloride (CAS 389574-19-0) is a small molecule inhibitor that targets platelet activation by antagonizing the P2Y12 adenosine diphosphate (ADP) receptor on platelet surfaces By inhibiting this receptor prasugrel impedes ADP-mediated platelet aggregation a critical process in thrombus formation In biochemical assays prasugrel hydrochloride demonstrates an IC50 of 1 8 M for platelet inhibition This compound is utilized in biomedical research to investigate platelet signaling pathways and to model antithrombotic interventions in vitro

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3,079

U.S. Pharmacopeia Formic Acid (1.2 mL/ampule; 3 ampules) | 64-18-6 | MFCD00003297

Formic Acid (1.2 mL/ampule; 3 ampules) | Mol Wt: 46.025 | 64-18-6 | MFCD00003297 |

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3,080

Apexbio Technology LLC Tiglic acid 80-59-1 100mg

Tiglic acid (CAS 80-59-1) is an unsaturated monocarboxylic acid found in natural sources such as Croton oil functioning as a plant-derived metabolite Studies have demonstrated that tiglic acid modulates specific signaling pathways and enzymatic activities within cells thereby influencing key biological processes Owing to its capacity to regulate cell signaling tiglic acid has been utilized in biomedical research related to cancer and inflammatory conditions serving as a valuable tool for investigating disease mechanisms and potential therapeutic strategies

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3,081

Apexbio Technology LLC CTOP TFA 1mg

CTOP TFA is a small-molecule antagonist targeting the -opioid receptor (MOR) It is designed to selectively inhibit MOR thereby regulating opioid receptor-mediated neural signaling pathways CTOP TFA exerts its biological activity primarily through specific interaction with and inhibition of MOR in the central nervous system Based on these pharmacological properties CTOP TFA holds research potential in investigating pain perception analgesia tolerance dependence neurotransmitter release stress responses and emotional regulation

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3,082

Apexbio Technology LLC ENMD-2076 L-(+)-Tartaric acid 1291074-87-7 50mg

ENMD-2076 L- plus -Tartaric acid is a small-molecule inhibitor targeting Aurora kinase A and B It is designed to inhibit the activity of these kinases thereby regulating cell cycle progression and mitotic processes ENMD-2076 L- plus -Tartaric acid exerts its biological activity primarily through the inhibition of Aurora kinase A and B with IC50 values of approximately 14 nM and 350 nM respectively In cell-based studies ENMD-2076 inhibits various breast cancer cell lines suppresses colony formation and induces G2 phase cell-cycle arrest Based on these pharmacological properties ENMD-2076 L- plus -Tartaric acid holds research potential in breast and hematological malignancies

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3,083

Apexbio Technology LLC Imidazole-4(5)-acetic Acid Hydrochloride 3251-69-2 500mg

Imidazole-4(5)-acetic Acid Hydrochloride (CAS 3251-69-2) is a small molecule utilized in biomedical research for its capacity to modulate specific enzyme activities Experimental studies indicate that this compound influences intracellular signaling pathways and metabolic processes thereby affecting various cellular functions It is frequently employed in neuroscience and metabolic regulation research to investigate its effects on physiological and pathological mechanisms Its modulatory properties make it a valuable tool for exploring the biochemical basis of cellular metabolism and neural activity